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Choosing an antihistamine for dogs can be a ponderous trial and error procedure. Yet, it is necessary for your vet to be confident the best antihistamine is found. Allergies take time to develop, but most dogs that develop an allergy do so between the ages of one and three years old. Of course other dogs may generate an allergy much later, at perhaps six years old. In fact you never know when a dog may come down with an allergy. An itching dog is never a fair sight and you must perpetually be on the lookout for an allergy problem.